Pipeline

Solutions for unmet medical needs

We are advancing a pipeline of allogeneic, off-the-shelf virus-specific T cell (VST) therapies to treat or prevent life-threatening viral diseases with limited to no treatment options in immunocompromised patients.
Definitions
Allo-HCT: allogeneic HCT; Auto-HCT: autologous HCT; POC: Proof-of-concept; High-risk general population: immunocompromised cancer patients, the elderly and very young.

Expanded Access Policy

Enrolling in a clinical trial is the most common way that persons who seek access to an investigational drug may receive that drug, and AlloVir’s clinical studies should be the primary route by which patients receive access to AlloVir’s investigational drug(s).

We treat individuals at high risk

Our allogeneic, off-the-shelf VST candidates benefit patients with T cell deficiencies, including transplant recipients, immunocompromised cancer patients, the elderly and the very young, who are at a higher risk of the devastating consequences of viral diseases.
Life-Threatening Viral Infections
  • Adenovirus
  • BK Virus
  • Cytomegalovirus
  • Epstein-Barr Virus
  • Human Herpesvirus-6
  • JC Virus
  • Human Metapneumovirus
  • Influenza Virus
  • Parainfluenza Virus
  • Respiratory Syncytial Virus
  • Hepatitis B Virus
organ diseases due to uncontrolled viral diseases
Brain
Severe encephalitis, seizure, memory defect, progressive multifocal leukoencephalopathy
Kidneys
Nephritis, acute / chronic renal failure, end-stage renal disease
Malignancy
Kaposi sarcoma, primary effusion lymphoma (PEL)
Liver
Chronic hepatitis, liver cirrhosis, hepatocellular carcinoma
Lungs
Pneumonia, bronchitis, respiratory failure
Small/Large Intestine
Colitis, ulceration / perforation, intestinal bleeding
Bladder
Severe hemorrhagic cystitis, urinary obstruction, cystectomy
Eyes
Retinitis, blindness
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AlloVir does not control and is not responsible for the content on the website you are about to visit. AlloVir is providing this link as a convenience, and this link does not imply AlloVir’s endorsement of any material on the website you are about to visit. Do you wish to continue?
AlloVir does not control and is not responsible for the content on the website you are about to visit. AlloVir is providing this link as a convenience, and this link does not imply AlloVir’s endorsement of any material on the website you are about to visit. Do you wish to continue?